Botox vs. Dysport vs. Jeuveau vs. Xeomin, explained.

"Which one is best?" might be the question I answer most in the treatment room. The honest answer: all four are excellent, all four are FDA approved, and the differences are smaller than the internet makes them sound. But the differences are real, and understanding them helps you have a smarter conversation with your injector. Here is how I explain it to my own patients.

First, what they have in common

Botox, Dysport, Jeuveau and Xeomin are all botulinum toxin type A. They work the same way: a precise, tiny dose relaxes the specific muscles whose repeated contractions crease the skin, which softens lines on the forehead, between the brows, and around the eyes. Results from any of them begin within days, look complete around two weeks, and last roughly three to four months. Injected conservatively by an experienced medical provider, your face still moves. It just reads calmer and more rested.

Botox

Botox is the original and the household name, on the market for cosmetic use since 2002. It is the most studied of the four and the standard against which the others are measured. For most patients it produces a reliable, predictable result with onset around three to five days. Because the name has become shorthand for the entire category, most people who ask for "Botox" are really asking for a neurotoxin treatment, whichever brand ends up in the syringe.

Dysport

Dysport tends to kick in a little faster, with many patients noticing movement changes in two to three days. It also spreads slightly more from each injection point, which can be an advantage in broader areas like the forehead, where a soft, diffuse effect looks the most natural. Dysport is dosed on its own unit scale, so comparing "units" of Dysport to units of other brands is apples to oranges. This is one reason per-unit price shopping between brands misleads people, and it deserves its own article. In fact, it has one.

Jeuveau

Jeuveau is the newest of the four, nicknamed "Newtox" when it launched in 2019, and it is the only one developed purely for aesthetics rather than adapted from medical uses. In practice it performs very similarly to Botox, with comparable dosing and onset. Many of our patients love it, and its loyalty program makes it a favorite for people who maintain a regular tox schedule.

Xeomin

Xeomin is often called the "naked" toxin because it is purified down to the active molecule without the accessory proteins the other brands carry. In theory, fewer complexing proteins may lower the chance of the body developing resistance over years of treatment, which is why we sometimes suggest it for long-term tox users who feel their results have gotten shorter-lived. It is also a thoughtful choice for patients who simply prefer the most stripped-down formulation.

Why Üesthetics carries Jeuveau, Dysport and Xeomin

We stock three of the four on purpose. Between Dysport's fast onset and soft spread, Jeuveau's modern aesthetics-first profile, and Xeomin's purified formulation, we can match the product to the patient instead of making every face fit one vial. And because all of these perform at parity with the original in day-to-day practice, nobody is missing out on anything by not seeing the Botox brand name on our shelf. What matters far more than the brand is the injector: assessment, dosing and placement are where results are actually made.

So which one should you choose?

Come in with your goals, not a brand. In your consultation we look at your anatomy, how your muscles move, your history with tox if you have one, and your budget, then recommend the product and dose that fits. First-timers often start lighter and build. Longtime tox users sometimes switch brands to see if another suits them better. Both are completely reasonable paths, and consultations here are complimentary, so it costs nothing to ask.

You can read more about our approach on the neurotoxins treatment page, or estimate your cost in about a minute with the price estimator.

Ready to talk it through?

Consultations at Üesthetics are complimentary and pressure-free. You can book online anytime, browse our full service menu, or build your own estimate with our price estimator.

This article is for education only and is not medical advice. Whether a treatment is right for you depends on your health history and goals, which is exactly what a consultation is for.